“As a co-founder of Heptares, I am very proud to have been associated with building a team of talented scientists over the past decade that has made many important breakthroughs in the field of GPCR stabilization and structure-based drug design, a unique technology that now underpins Sosei’s powerful drug discovery capability,” said Dr. Marshall. “With the team in excellent hands, I feel the time is right for me to move on to new challenges and I wish everyone at Sosei the best for what looks set to be an exciting future for the Company.”
Peter Bains, Chief Executive Officer of Sosei, added: “Fiona has been a pivotal figure in advancing the science of GPCR stabilization, and in creating Sosei StaR® technology, a legacy that in time we believe will lead to the development of new and innovative medicines. Thanks to Fiona, we have built a deep pool of talented scientists who will continue to carry on our world-leading work in GPCR-focused drug discovery and development and execute on our vision to become a fully integrated global biotechnology company. The Board and I express our sincere thanks to Fiona for her significant contributions to Sosei and wish her the very best in her exciting new role.”
Sosei’s R&D activities will continue under the leadership of Dr. Malcolm Weir, co-founder and Chief Executive Officer of Heptares, and Executive Vice President and Chief R&D Officer of Sosei.
Separately, and reflecting the progress of Sosei’s proprietary pipeline of drug development candidates, Dr. Tim Tasker is promoted to the Executive management team of Sosei as an Executive Vice President and Chief Medical Officer (CMO). Dr. Tasker will continue to report to Dr. Malcolm Weir, Chief R&D Officer.
Peter Bains commented: “Tim’s promotion is thoroughly deserved and reflects the increasing importance of clinical development expertise in the team. This expertise is crucial to supporting our partnered programs and more importantly to drive our proprietary programs, of which we plan to advance at least six candidates into clinical studies over the next two years, including HTL0018318, our selective muscarinic M1 agonist, which we expect to start a Phase 2 trial in patients with dementia with Lewy bodies (DLB) in Japan during this year.”